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HEADACHE: Dogbane (Apocynum androsaemifolium L.) root was dried and pulverized. This herb was used for a headache and for a serious affection of the nerves, the headache being a symptom. May also be accompanied by outh twitches, dizziness, and in the case of insanity another herb was added. There were 5 ways of administering this herb.

1. 4 pieces of the dried root about the size of a pea were pulverized and the dry powder was snuffed up the nose.
2. The powdered root was put on hot stones. The patient's head was covered and the fumes inhaled.
3. The powdered root was moistened with lukewarm water and applied to incisions on the temples by eans of soft duck down.
4. Dried, chewed.
5. A decoction make and taken internally